Products
| Order NO.: D260254-0100 | CAS : |
Anti-EIF4G2 rabbit polyclonal antibody
| Synonym | ||
| Storage | -20°C | |
| Categories | Primary Antibodies |
| Cat NO. | Package | Price(USD) |
| D260254-0100 | 100 UL | 250.0 |
| Bulk orders? | ||
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Background: Translation initiation is mediated by specific recognition of the cap structure by eukaryotic translation initiation factor 4F (eIF4F), which is a cap binding protein complex that consists of three subunits: eIF4A, eIF4E and eIF4G. The protein encoded by this gene shares similarity with the C-terminal region of eIF4G that contains the binding sites for eIF4A and eIF3; eIF4G, in addition, contains a binding site for eIF4E at the N-terminus. Unlike eIF4G, which supports cap-dependent and independent translation, this gene product functions as a general repressor of translation by forming translationally inactive complexes. In vitro and in vivo studies indicate that translation of this mRNA initiates exclusively at a non-AUG (GUG) codon. Alternatively spliced transcript variants encoding different isoforms of this gene have been described. Properties Host Rabbit Conjugate Human, Mouse nameofantibody EIF4G2
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