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Order NO.: C610004-0010 | CAS : |
Recombinant Human Interleukin-2
Synonym | ||
Storage | -20°C | |
Categories | Recombination Proteins |
Cat NO. | Package | Price(USD) |
C610004-0010 | 10 UG | 105.0 |
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Source Escherichia coli. Properties summary IL-2 is a powerful immunoregulatory lymphokine produced by T-cells in response to antigenic or mitogenic stimulation. It is expressed by CD4+ and CD8+ T cells, γδ T cells, B cells, dendritic cells, and eosinophils. IL-2/IL-2R signaling is required for T-cell proliferation and other fundamental functions which are essential for the immune response. The receptor for IL-2 consists of three subunits (55 kDa IL-2Rα, 75 kDa IL-2Rβ, and 64 kDa common gamma chain γc/IL-2Rγ) that are present on the cell surface in varying preformed complexes. Mature human IL-2 shares 56 % and 66 % amino acid sequence identity with mouse and rat IL-2, respectively. Human and mouse IL-2 exhibit cross-species activity.
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